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Due to its rapid, continuous, and reproducible abilities, the spray drying technique is very appealing for the laboratory and in the industry. This technique is scalable without making any major modifications. In addition, the final drying step is required in other techniques such as emulsion/solvent evaporation is not needed for spray drying. The technique greatly depends on the fulfillment of two conditions: scalability and cost-effectiveness. Another advantage spray drying has is the possibility to dry a large spectrum of compounds without any major detrimental effects. Heat sensitive substances are included in the spectrum. This is due to the atomization of the liquid which forms into small droplets with high surface area to volume ratio and therefore, leads to a very fast solvent evaporation. An example of this is during a co-current flow setup, the product temperature is 10 to 20 °C below the air outlet temperature. Although the droplets could be exposed to high temperature during the drying process, the exposure time is extremely short. It is usually in the range of seconds or even milliseconds. Under such conditions, drug degradation is not anticipated.

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